Curriculum vitae
EDUCATION AND RESEARCH EXPERIENCE
2018- Assistant Professor in Infectious Disease Modelling
Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine
2015-2018 Senior Mathematical Modeller
Public Health England
2016-2018 Honorary Research Fellow
Imperial College London, Department of Infectious Disease Epidemiology
2015- Visiting Research Fellow
University of Cambridge, Department of Applied Mathematics and Theoretical Physics
2012-2014 AXA Research Fellow
University of Cambridge
Awarded a fellowship to study self-enforcing international agreements in regional control of immunizing infections.
2009-2012 Postdoctoral Research Associate and Lecturer
Princeton University
Developed new theoretical framework focusing on economics of disease eradication. Collaborated with other postdocs to apply the age-structured epidemic framework to available data on rubella.
2007-2009 UNESCO-L'Oréal "For Women in Science" Postdoctoral Fellow
Pennsylvania State University
Developed new theoretical framework for determining optimal control strategies for infectious diseases with focus on measles.
2001-2007 PhD in Biological Oceanography
Massachusetts Institute of Technology / Woods Hole Oceanographic Institution
Doctorate thesis, advisor Dr. M. Neubert: “Population interactions: hosts and pathogens, prey and predators" [pdf from mit.edu]
Developed and analyzed epidemic models for phocine distemper virus dynamics and fitted them to available epizootic data.
Developed new dispersal models for predator-prey metapopulations.
1996-2001 dipl. ing. biology - ecology
University of Zagreb, Croatia
Thesis in ecology: “The effects of dispersal delays on dynamics of predator-prey metapopulations”
1994-1996 International Baccalaureate
XV. Gimnazija, Zagreb, Croatia
Extended essay in mathematics: “Approximation of irrational numbers using continued fractions applied on improvement of Bach’s well-tempered scale”
TEACHING EXPERIENCE
June 2016 London School of Hygiene and Tropical Medicine
Tutor in Introduction to Infectious Disease Modelling and its Applications
2012-2014 Christ’s College, University of Cambridge
Supervisor in Part 1A Mathematical Biology
Fall 2011 Princeton University
Lecturer in Theoretical Ecology, advanced undergraduate course
Developed lectures, recruited 3 guest speakers, supervised one teaching assistant, wrote exams, oversaw group projects designed and exam questions.
Spring 2010 Princeton University
Guest lecturer in Disease Ecology, Economics and Policy, and Theoretical Biology classes.
June 2009 Max Planck Institute for Demography
Assistant Lecturer in Frontiers of Formal Demography, summer school
Helped develop and teach a course for matrix model approaches in demography.
Fall 2007 Pennsylvania State University
Co-lecturer in Population Biology, graduate course
Developed, prepared and held a block of 5 lectures, designed homework problems and exam questions.
PUBLICATIONS
Klepac, P. (2017) Linking levels of life: Comment on “Physics of metabolic organization” by Marko Jusup et al., Physics of Life Reviews, http://dx.doi.org/10.1016/j.plrev.2017.01.024 [read here]
Klepac, P., Megiddo, I., Grenfell, B. and Laxminarayan, R. (2016) Self-enforcing regional vaccination agreements. Journal of the Royal Society Interface 13: 20150907
Heesterbeek, H., Anderson, R. M., Andreasen, V., Bansal, S., De Angelis, D., Dye, C., Eames, K. T. D., Edmunds, W. J., Frost, S. D. W., Funk, S., Hollingsworth, T. D., House, T., Isham, V., Klepac, P., Lessler, J., Lloyd-Smith, J. O., Metcalf, C. J. E., Mollison, D., Pellis, L., Pulliam, J. R. C., Roberts, M. G., Viboud, C. and Isaac Newton Institute IDD Collaboration (2015) Modeling infectious disease dynamics in the complex landscape of global health. Science, 347(6227), aaa4339–aaa4339. doi:10.1126/science.aaa4339
Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P. and Heesterbeek, J.A.P. (2015) Challenges in modelling infectious disease dynamics: preface, Epidemics, 10: iii-iv.
Klepac, P., Sebastian, F., Hollingsworth, T. D., Metcalf, C. J. E. and Hampson, K. (2015) Six challenges in eradication of infectious diseases. Epidemics, 10: 97-101. [open access]
Funk, S., Bansal, S., Bauch, C. T., Eames, K. T. D., Edmunds, W. J., Galvani, A. and Klepac, P. (2015) Challenges in modelling the dynamics of behaviour towards infectious diseases. Epidemics, 10, 21-25. [open access]
Klepac, P., Metcalf, C. J. E., McLean, A. and Hampson, K. (2013) Towards the endgame and beyond: complexities and challenges for the elimination of infectious diseases. Philosophical Transactions of the Royal Society B 368: 20120137. [open access]
Henderson, D. A. and Klepac, P. (2013) Lessons from the eradication of smallpox: an interview with DA Henderson. Philosophical Transactions of the Royal Society B 368: 20130113. [open access]
Metcalf, C. J. E., Cohen, C., Lessler, J., McAnerney, J. M., Ntshoe, G. M., Puren, A., Klepac, P., Tatem, A., Grenfell, B. T., Bjørnstad. O. N. 2012. Implications of spatially heterogeneous vaccination coverage for the risk of congenital rubella syndrome in South Africa. Journal of the Royal Society Interface 10: 20120756.
Klepac, P., Metcalf, C.J.E., Bjørnstad, O. N. and Grenfell, B.T. 2012. Optimizing reactive responses to outbreaks of immunizing infections: balancing case management and vaccination. PLOS ONE 8:e41428. [open access]
Metcalf, C.J.E., Lessler, J., Klepac, P., Cutts, F., and Grenfell, B.T. 2012. Impact of birth rate, seasonality and transmission rate on minimum levels of coverage needed for rubella vaccination. Epidemiology and Infection 140: 2290-2301.
Metcalf, C.J.E., Lessler, J., Klepac, P., Morice, A., Grenfell, B.T. and Bjørnstad, O. N. 2012. Structured models of infectious disease: Inference with discrete data. Theoretical Population Biology 82: 275:282.
Klepac, P., Laxminarayan, R. and Grenfell, B. T. 2011. Synthesizing epidemiological and economic optima for control of immunizing infections. Proceedings of the National Academy of Sciences 108: 14366–14370. [open access]
Klepac, P. and Caswell, H. 2011. The stage-structured epidemic: linking disease and demography with a multi-state matrix model approach. Theoretical Ecology 4: 301-319. [pdf from mblwhoilibrary.org]
Metcalf, C. J. E., Bjørnstad, O. N., Ferrari, M., Klepac, P., Bharti, N., Lopez-Gatell, H. and Grenfell, B. T. 2011. The epidemiology of rubella in Mexico: seasonality, stochasticity and regional variation. Epidemiology and Infection 139: 1029-1038.
Metcalf, C. J. E., Klepac, P., Ferrari, M., Grais, R. F., and Grenfell, B. T. 2011. Modelling the first dose of measles vaccination: the role of maternal immunity, demographic factors, and delivery systems. Epidemiology and Infection 139: 265-274.
Klepac, P., Pomeroy, L. W., Bjørnstad, O. N., Kuiken, T., Osterhaus, A. D. M. E., and Rijks, J. M. 2009. Stage-structured transmission of phocine distemper virus in the Dutch 2002 outbreak. Proceedings of the Royal Society B 276: 2469-2476.
Klepac, P., Neubert, M. G., and van den Driessche, P. 2007. Dispersal delays and the paradox of enrichment. Theoretical Population Biology 71: 436-444. [pdf from mblwhoilibrary.org]
Rapatski, B., Klepac, P., Dueck, S., Liu, M. and L. I. Weiss. 2006. Mathematical epidemiology of HIV/AIDS in Cuba during the period 1986-2000. Mathematical Biosciences and Engineering 3: 545-556.
Neubert, M. G., Klepac, P. and van den Driessche, P. 2002. Stabilizing dispersal delays in predator-prey metapopulation models. Theoretical Population Biology 61: 339-347. [pdf from whoi.edu]
AWARDS AND FELLOWSHIPS
2013 Sackler and Cambridge Foundation Research Fellowship, Christ’s College
2012 AXA Research Fund Fellowship
2007 UNESCO-L’Oréal Fellowship for Women in Science
2005 Best poster award, European Conference on Mathematical and Theoretical
Biology, Dresden, Germany
Bayesian Methods for Population Ecology, University of Cambridge
European Society for Mathematical and Theoretical Biology Travel Fund
Society for Mathematical Biology Landahl Travel Grant
Ocean Ventures Fund Award
2004 Special Program on Infectious Diseases Summer School, Banff, Canada
1999 “Best Presentation by a Young Scientist” Award, 2nd European Ecological
Modelling Conference, Pula, Croatia
Summer Student Fellowship, Woods Hole Oceanographic Institution
EDITING EXPERIENCE
2013-2014 Epidemics, Journal of Infectious Disease Dynamics
Guest editor
2013-2013 Philosophical Transactions of the Royal Society B
Guest editor
Proposed, edited and compiled a special issue entitled “Towards the endgame and beyond: complexities and challenges for the elimination of infectious diseases” with two colleagues.
MEDIA COVERAGE
“A quoi sert la vaccination?”, L’Express Chercheours d’actu blog, April, 2014.
“Cooperation is crucial to eliminate infectious disease”, Laxminarayan, Klepac & Grenfell, Science and Development Network, June 2012.
"Mathematics and epidemiology:Neighbourly advice”, The Economist, Science and Technology blog, January 2012.
"Love thy neighbor(s): The Need for Herd Immunity”, Center for global development, Global Health Policy blog, January 2012.
SELECTED INVITED TALKS AND SEMINARS
Cooperation and control of infectious diseases, Centre for Mathematical Biology Seminar, University of Bath, February 2017.
Incorporating demographic heterogeneity in epidemiological models for better public health decision-making, Modelling infectious disease minisymposium at ECMTB 2016, Nottingham, UK, July 2016.
Heterogeneity in influenza dynamics and modelling. Symposium on The impact of mathematical modelling of influenza: better decisions for Public Health, Public Health England, London, UK, January 2016.
The spread and control of infectious diseases. Emerging Research Seminar Series, Christ’s College, Cambridge, UK, November 2014.
Eradication efforts in the 21st century: marriage of epidemiology and economics. Warwick Infectious Disease Epidemiology Research Seminar, University of Warwick, UK, December 2013.
International agreements for optimal disease control. MBI workshop: rapid evolution and sustainability, Mathematical Biosciences Institute, Ohio State University, Columbus, OH, US, October 2013.
International agreements and optimal control of immunizing infections. Infectious Disease Dynamics Workshop, Isaac Newton Institute for Mathematical Sciences, Cambridge, UK, August 2013.
Free-ride or cooperate? Economic incentives and immunizations. Ecology and Evolution of Infectious Diseases, Pennsylvania State University, University Park, May 2013.
To eradicate or not to eradicate: economic optima for spatial immunizing infections. Natural Resources Modeling Symposium, Joint Mathematics Meetings, Boston, January 2012.
Synthesizing economic and epidemic optima for spatial vaccination programs. University of Oxford. September 2011.
Economic and epidemic optima for control of immunising infections. Queens’ College, University of Cambridge. September 2011.
Laxminarayan, R., Grenfell, B. Economic optima for spatial vaccination programs. “Disease in motion”, Princeton University. November 2010.
Population modeling with disease parameters to achieve more realistic outcomes. Symposium on “Pathology and Medicine in Marine Ecosystem Conservation”, International Marine Conservation Congress. May 2009.
Vaccine Supply Logistics Modeling. World Health Organization. Geneva, Switzerland. February 2009.
Modeling and control of infectious diseases. Ruđer Bošković Institute, Zagreb, Croatia. September 2008.
Phocine distemper virus outbreaks in European harbor seals. Ecological seminar at Pennsylvania State University. November 2007.
The dynamics of phocine distemper virus epizootics in European harbor seals. Harvard School of Public Heath. April 2007.
Seasonal haul-out behavior and the dynamics of the phocine distemper virus, Center for Infectious Disease Dynamics Seminar, Pennsylvania State University. May 2006.
Seasonal haul-out behavior and the dynamics of the phocine distemper virus, Biology Department Seminar, Woods Hole Oceanographic Institution. April 2006.
Sezonsko ponašanje običnih tuljana i matematička epidemiologija virusa Phocine distemper, 29. Kolokvij Hrvatskog društva za teorijsku i matematičku biologiju. University of Zagreb, Croatia. January 2006.
Epidemiology of the harbour seal plague, The Göteborg Network for Theoretical Biology, Göteborg University, Sweden. September 2005.
ORGANIZATIONAL SKILLS
2011-2012 Chair of EEB Society of Fellows
Princeton University
Coordinated scientific and social events for postdoctoral fellows.
2010 Symposium co-organizer
Ecological Society of America Annual Meeting, Pittsburgh
“The Invasion Ecology of the Disease: Understanding the Drivers of Microbial Community Assembly and Host-Microbe Dynamics in the Human Body”
June 2008 Workshop Organizer
Center for Infectious Disease Dynamics, Pennsylvania State University
Designed and organized a 2-day international workshop on “Control and management of infectious diseases” with aims to synthesize and improve the latest control and management methods in disease control and prevention.
PROFESSIONAL AND SCIENTIFIC MEMBERSHIPS
Ecological Society of America
European Society for Mathematical and Theoretical Biology
American Mathematical Society
Society for Mathematical Biology
Natural Resource Modelling
Reviewer for: American Naturalist, Journal of Mathematical Biology, Journal of the Royal Society Interface, Mathematical Biosciences, Mathematical Medicine and Biology, PLoS Computational Biology, Proceedings of the National Academy of Sciences, SIAM, SIAP
SKILLS AND LANGUAGES
Languages: Croatian (native), English (fluent), German (intermediate), French (basic)
Photography: Fowler Art Show 2006
Boat Leader License (certified in 1994)
Scuba diving (NAUI certified in 2000)