1. Klepac, P. (2017) Linking levels of life: Comment on “Physics of metabolic organization” by Marko Jusup et al., Physics of Life Reviews, [read here]

  2. Klepac, P., Megiddo, I., Grenfell, B. and Laxminarayan, R. (2016) Self-enforcing regional vaccination agreements. Journal of the Royal Society Interface, 1320150907. [read here]

  3. Heesterbeek, H., Anderson, R. M., Andreasen, V., Bansal, S., De Angelis, D., Dye, C., Eames, K. T. D., Edmunds, W. J., Frost, S. D. W., Funk, S., Hollingsworth, T. D., House, T., Isham, V., Klepac, P., Lessler, J., Lloyd-Smith, J. O., Metcalf, C. J. E., Mollison, D., Pellis, L., Pulliam, J. R. C., Roberts, M. G., Viboud, C. and Isaac Newton Institute IDD Collaboration (2015) Modeling infectious disease dynamics in the complex landscape of global health. Science, 347(6227), aaa4339–aaa4339. doi:10.1126/science.aaa4339

  4. Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P. and Heesterbeek, J.A.P. (2015) Challenges in modelling infectious disease dynamics: preface, Epidemics, 10: iii-iv

  5. Klepac, P., Sebastian, F., Hollingsworth, T. D., Metcalf, C. J. E. and Hampson, K. (2015) Six challenges in eradication of infectious diseases. Epidemics, 10: 97-101. [open access]

  6. Funk, S., Bansal, S., Bauch, C. T., Eames, K. T. D., Edmunds, W. J., Galvani, A. and Klepac, P. (2015) Nine challenges in incorporating the dynamics of behaviour in infectious disease models. Epidemics, 10: 21-25. [open access]

  7. Klepac, P., Metcalf, C. J. E., McLean, A. and Hampson, K. (2013) Towards the endgame and beyond: complexities and challenges for the elimination of infectious diseases. Philosophical Transactions of the Royal Society B 368: 20120137. [open access]

  8. Henderson, D. A. and Klepac, P. (2013) Lessons from the eradication of smallpox: an interview with DA Henderson. Philosophical Transactions of the Royal Society B 368: 20130113. [open access]

  9. Metcalf, C. J. E., Cohen, C., Lessler, J., McAnerney, J. M., Ntshoe, G. M., Puren, A., Klepac, P., Tatem, A., Grenfell, B. T., Bjørnstad. O. N. (2012) Implications of spatially heterogeneous vaccination coverage for the risk of congenital rubella syndrome in South Africa.  Journal of the Royal Society Interface 10: 20120756.

  10. Klepac, P., Metcalf, C.J.E., Bjørnstad, O. N. and Grenfell, B.T. (2012) Optimizing reactive responses to outbreaks of immunizing infections: balancing case management and vaccination. PLOS ONE 8:e41428. [open access]

  11. Metcalf, C.J.E., Lessler, J., Klepac, P., Cutts, F., and Grenfell, B.T. (2012) Impact of birth rate, seasonality and transmission rate on minimum levels of coverage needed for rubella vaccination. Epidemiology and Infection 140: 2290-2301.

  12. Metcalf, C.J.E., Lessler, J., Klepac, P., Morice, A., Grenfell, B.T. and Bjørnstad, O. N. (2012) Structured models of infectious disease: Inference with discrete data. Theoretical Population Biology 82: 275:282.

  13. Klepac, P., Laxminarayan, R. and Grenfell, B. T. (2011) Synthesizing epidemiological and economic optima for control of immunizing infections. Proceedings of the National Academy of Sciences 108: 14366–14370. [open access]

  14. Klepac, P. and Caswell, H. (2011) The stage-structured epidemic: linking disease and demography with a multi-state matrix model approach. Theoretical Ecology 4: 301-319. [pdf from]

  15. Metcalf, C. J. E., Bjørnstad, O. N., Ferrari, M., Klepac, P., Bharti, N., Lopez-Gatell, H. and Grenfell, B. T. (2011)  The epidemiology of rubella in Mexico: seasonality, stochasticity and regional variation. Epidemiology and Infection 139: 1029-1038.

  16. Metcalf, C. J. E., Klepac, P., Ferrari, M., Grais, R. F., and Grenfell, B. T. (2011) Modelling the first dose of measles vaccination: the role of maternal immunity, demographic factors, and delivery systems. Epidemiology and Infection 139: 265-274.

  17. Klepac, P., Pomeroy, L. W., Bjørnstad, O. N., Kuiken, T., Osterhaus, A. D. M. E., and Rijks, J. M. (2009) Stage-structured transmission of phocine distemper virus in the Dutch 2002 outbreak. Proceedings of the Royal Society B 276: 2469-2476.

  18. Klepac, P., Neubert, M. G., and van den Driessche, P. (2007) Dispersal delays and the paradox of enrichment. Theoretical Population Biology  71: 436-444. [pdf from]

  19. Rapatski, B., Klepac, P., Dueck, S., Liu, M. and L. I. Weiss. (2006) Mathematical epidemiology of HIV/AIDS in Cuba during the period 1986-2000. Mathematical Biosciences and Engineering 3: 545-556.

  20. Neubert, M. G., Klepac, P. and van den Driessche, P. (2002) Stabilizing dispersal delays in predator-prey metapopulation models. Theoretical Population Biology 61: 339-347. [pdf from]


  1. Special issue of Epidemics “Challenges in modelling infectious disease dynamics”, Edited by James Lloyd-Smith, Denis Mollison, Jessica Metcalf, Petra Klepac and Hans Heesterbeek.

  2. Special issue of the Philosophical Transactions of the Royal Society “Towards the endgame and beyond: complexities and challenges for the elimination of infectious diseases”, compiled and edited by Petra Klepac, C. Jessica E. Metcalf and Katie Hampson


  1. Klepac, P. "Interacting populations: Hosts and Pathogens, Prey and Predators", Massachusetts Institute of Technology and Woods Hole Oceanographic Institution. 2007.   [pdf from]